د.سلام بدر مشرف
عدد الرسائل : 14 تاريخ التسجيل : 05/10/2008
| موضوع: Treatment of allergic bronchopulmonary aspergillosis (ABPA) in CF with anti-IgE antibody (omalizumab) الخميس نوفمبر 27, 2008 1:09 am | |
| Treatment of allergic bronchopulmonary aspergillosis (ABPA) in CF with anti-IgE antibody (omalizumab)
Allergic bronchopulmonary aspergillosis (ABPA) results from IgE induced pulmonary response to aspergillus species. Recognition and management of ABPA is challenging in cystic fibrosis (CF) patients because changes in symptoms, lung function and chest radiograph are similar to that seen in CF related pulmonary infection. Standard therapy for ABPA includes systemic steroids and adjunctive use of antifungal agents. Little has been published regarding the use of monoclonal anti-IgE antibody in those with ABPA. We report a CF patient with her third exacerbation of ABPA who was treated with monoclonal anti-IgE (omalizumab) antibody; she had unfavorable side effects with prednisone therapy. This therapy resulted in improvement of pulmonary symptoms and lung function not achieved with antibiotics or prednisone alone. Pediatr Pulmonol. (c) 2008 Wiley-Liss, Inc.
Source: Pediatr Pulm | Posted 1 week ago
| |
|
dr.aljuraisy Admin
عدد الرسائل : 4046 العمل/الترفيه : طبيب أختصاصي طب الأطفال وحديثي الولادة المزاج : الحمد لله جيد تاريخ التسجيل : 15/09/2008
| موضوع: رد: Treatment of allergic bronchopulmonary aspergillosis (ABPA) in CF with anti-IgE antibody (omalizumab) الخميس نوفمبر 27, 2008 1:24 am | |
| شكرا لك د- سلام معلومة حديثة ومفيدة ممنونين _________________ <p> خالص شكري وتقديري د-عبد الهادي الجريصي </p> <p> </p> | |
|