dr.alatwane مشرف
عدد الرسائل : 28 العمر : 54 تاريخ التسجيل : 17/09/2008
| موضوع: New Treatment for Bronchiolitis in Infants الخميس مايو 14, 2009 4:06 pm | |
| New Treatment for Bronchiolitis in Infants
Nebulized 3% saline in conjunction with bronchodilators shortened hospital stay and lowered clinical severity.
Current therapy for treating bronchiolitis in infants is only supportive; however, in several earlier studies, researchers have evaluated whether administering nebulized 3% saline might reduce severity and speed recovery. In a meta-analysis conducted by the Cochrane Collaboration, investigators analyzed four randomized, controlled trials (RCTs) that involved 189 inpatients and 65 outpatients (age, <24 months).
In three inpatient RCTs, infants assigned to 3% saline had a significantly shorter mean length of stay (by 1 day) than infants who received 0.9% normal saline. In two inpatient RCTs and the single outpatient trial, infants who received 3% saline, versus those who received 0.9% saline, had a significantly lower mean postinhalation clinical score during the first 3 days of treatment.
Comment: These results are encouraging, but some caveats should be noted. In three of the four trials, bronchodilators (epinephrine and terbutaline) were added to the 3% saline regimens. In the other trial, physicians could opt to add albuterol and racemic epinephrine (used in 37% and 23% of children, respectively). Because the total number of patients was small, no meaningful data about side effects are available. Nevertheless, 3% saline, when combined with a bronchodilator, does seem to shorten length of hospital stay in children who are admitted with diagnoses of bronchiolitis.
— Howard Bauchner, MD
Published in Journal Watch Pediatrics and Adolescent Medicine May 13, 2009
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dr.aljuraisy Admin
عدد الرسائل : 4046 العمل/الترفيه : طبيب أختصاصي طب الأطفال وحديثي الولادة المزاج : الحمد لله جيد تاريخ التسجيل : 15/09/2008
| موضوع: رد: New Treatment for Bronchiolitis in Infants الخميس مايو 14, 2009 6:48 pm | |
| Thanks Dr.Salim for your nice issue which we facing commonly in our hosp. best regards
_________________ <p> خالص شكري وتقديري د-عبد الهادي الجريصي </p> <p> </p> | |
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